This is a histologically benign lesion with very aggressive local behavior. The pictures used in this presentation have been obtained from a number of sources. From 1962 to 1984, patients with juvenile nasopharyngeal angiofibroma jna were treated with megavoltage radiation therapy. Nasopharyngeal angiofibroma definition of nasopharyngeal. The management of juvenile nasopharyngeal angiofibroma jna has changed during the last decades but it still continues to be a challenge for the multidisciplinary head and neck surgical team. Ppt journal juvenile nasopharynx angiofibroma free download as powerpoint presentation. The tumor is locally aggressive and can invade into surrounding structures and cause significant complications. It is a highly vascularized slow growing tumor, but locally invasive and destructive. Juvenile nasopharyngeal angiofibroma is a benign but locally invasive tumor accounting for about 0. Infact hippocrates goes on to describe a polyp in the nose which weeped blood. Juvenile angiofibroma jna is a benign tumor that tends to bleed and occurs in the nasopharynx of prepubertal and adolescent males. Juvenile nasopharyngeal angiofibromas jna are a rare benign but locally aggressive vascular tumor. Call 4166330001 or email us today to find out the best angiofibroma treatment option for you.
Transnasal endoscopic surgery in juvenile nasopharyngeal. Juvenile nasopharyngeal angiofibroma is an uncommon benign tumour of the nasopharynx which arises in the region of the sphenopalatine foramen and it grows insidiously invading surrounding structures. The tumor contains many blood vessels and spreads within the area in which it. Nasopharyngeal angiofibroma symptoms aurora health care. Juvenile nasopharyngeal angiofibroma jna is a rare, benign, but locally aggressive tumor occurring almost exclusively in adolescent males. They often grow quickly during puberty, then slow down or stop growing entirely after adolescence. In 1906 chareau revived the interest in the study of juvenile nasopharyngeal angiofibroma. A juvenile nasopharyngeal angiofibroma jna is a noncancerous tumor made up of blood vessels that grow at the posterior aspect of the nose. Starting with a brief introduction to the history, etiology and relevant anatomy, the book goes on to discuss the pathology, clinical features and treatment of this. Nasopharyngeal angiofibroma introduction juvenile nasopharyngeal angiofibroma jna is a benign, but locally aggressive and extremely vascular head and neck neoplasm, occurring almost exclusively in the nasopharynx of adolescent males. Juvenile nasopharyngeal angiofibroma electronic journal of. Juvenile nasal angiofibroma jna is a rare sinonasal tumor that is found almost exclusively in adolescent and young adult males.
Juvenile nasopharyngeal angiofibroma radiology case. Patients usually present with nasal obstruction and epistaxis. Seventytwo patients with juvenile angiofibroma have been investigated by computerized tomography ct andor magnetic resonance imaging mri over a period of 20 years. Juvenile nasopharyngeal angiofibroma knowledge for. Some surgeons, however, do not routinely perform embolization preoperatively, finding that embolization is justified only in larger tumors therefore, all cases corresponded to snyderman grade iv table 4. Juvenile nasopharyngeal angiofibroma is a rare, highly luiz a cr, romualdo s lt, fava a s. Juvenile nasopharyngeal angiofibromas are a rare benign, but locally aggressive, vascular tumors that occur almost exclusively in young men on imaging, they present as a vividly enhancing softtissue masses centered on the sphenopalatine foramen. Ppt journal juvenile nasopharynx angiofibroma radiation. We report the case of a 17yearold male who presented in 1995 with a mass filling the left posterior nasal cavity. Pdf juvenile angiofibroma is a rare benign lesion originating from the pterygopalatine fossa with distinctive epidemiologic features and growth.
The management of juvenile angiofibroma ja has changed during the last decades but it still continues to be a challenge. It most commonly affects adolescent males and may grow into fissures of the. Juvenile nasopharyngeal angiofibroma is described as a rare and benign disease, which is mainly diagnosed in male adolescents. Although the use of nonsurgical therapies is described in the literature, surgery is currently considered the ideal treatment for.
Seven cases of biopsyproved juvenile nasopharyngeal angiofibroma are presented. Also known as fibrous papule common benign fibrohistiocytic tumor, usually on the face of middle aged persons and often on the nose some have postulated this lesion to be a hamartoma composed of perifollicular or interfollicular connective tissue and a hair follicular epithelial component j cutan pathol 2009. It was first described by hippocrates in the 5 th century bc. Examination under anesthesia and tomography and angiography were very rewarding in.
Home acta otorrinolaringologica espanola comprar tratamiento quirurgico del angiofibroma nasofaringeo juvenil en pacientes pediatricos. Juvenile nasopharyngeal angiofibroma jna is a benign neoplasm of the nasopharynx. Recently a changing trend has been seen in its epidemiology, pathogenesis, diagnosis, medical management, preoperative care, surgical management and postoperative care including radiotherapy. Angiofibroma removal in toronto dermatology centre is a commonly performed procedure with great results. It is almost exclusicely encountered in adolescent males 1. Licensed to youtube by the orchard music on behalf of. Pdf juvenile nasopharyngeal angiofibroma is tumour almost exclusively seen in adolescent males, constituting.
Angiofibroma nasofaringeo juvenil com extensao intradural. The typical patient is an adolescent male with a clinical history of recurrent epistaxis and nasal obstruction. Epidemiology juvenile nasopharyngeal angiofibromas. A male, 21 years of age, without relevant history, presented with left exophthalmos and diplopia in extreme gaze positions with 2 weeks evolution, without clinic of epistaxis or nasal obstruction. Common practice is to excise the tumor with open or endoscopic surgery. Juvenile nasopharyngeal angiofibroma jna jnas are wellvascularized benign lesions typically occurring in adolescent males. The most common presenting symptom is painless nasal obstruction or epistaxis. Juvenile nasopharyngeal angiofibroma surgical treatment in. Given its vascularity, prominent flow voids are seen on mri leading to a salt and pepper appearance.
Juvenile nasopharyngeal angiofibroma jna is a rare tumor that exhibits a predictable spreading pattern. Their use is purely for academic and teaching purposes. Adolescents and young adults between 14 and 25 years are affected, and there is a distinct male predominance. Nasopharyngeal angiofibroma is a histologically benign but locally aggressive vascular tumor of the nasopharynx that arises from the superior margin of the sphenopalatine foramen and grows in the back of the nasal cavity. Nasopharyngeal angiofibroma is usually encapsulated and composed of vascular tissue and fibrous stroma with coarse or fine collagen fibers. Juvenile nasopharyngeal angiofibroma radiology reference. Review article nasopharyngeal angiofibroma ashutosh hota. Endoscopic surgery in treatment of juvenile nasopharyngeal angiofibroma. Juvenile nasopharyngeal angiofibroma iowa head and neck. Juvenile nasopharyngeal angiofibroma is a very rare, highly vascular, uncapsulated and locally invasive tumor. In addition, the term nasopharyngeal is often used instead of nasal because angiofibromas that occur.
Juvenile nasopharyngeal angiofibroma jna represents. It is presented a case of juvenile nasopharyngeal angiofibroma in a patient with this pathology, from the clicial practice no. Pdf juvenile nasopharyngeal angiofibroma jna is a benign highly vascular tumor. Juvenile nasopharyngeal angiofibroma jna onset most commonly is in the second decade. A case of angiofibroma limited to the right posterior nasal cavity, nasopharynx, and pterygopalatine fossa was operated upon transnasally under endoscopic. Juvenile angiofibroma rads see also with virtual slide. The tumor usually arises in puberty and is more common in boys than in girls. Angiofibroma nasofaring juvenile free download as pdf file. Schuon et al reported on the immunohistochemical analysis of growth mechanisms in juvenile nasopharyngeal angiofibroma. Abstract juvenile nasopharyngeal angiofibroma is a benign vascularized tumor, locally invasive, originated in the sphenopalatine foramen. Radiologists prior knowledge on the tumors characteristics aids in establishing a diagnosis.
Shaheen in 1930 reported the first female patient with juvenile nasopharyngeal. Originating in the margin of the sphenopalatine foramen, it extends itself to the pterygopalatine fosse, paranasal sinus and nasal cavity, leading to symptoms. Toronto dermatology centre is located in toronto, ontario, and serves men and women in north york, vaughan, richmond hill, york, aurora. Differential diagnosis cellular angiofibroma surgical. Ppt juvenile nasopharyngeal angiofibroma powerpoint. It was friedberg who first used the term angiofibroma in 1940. Juvenile nasopharyngeal angiofibroma a free powerpoint ppt presentation displayed as a flash slide show on id. Juvenile nasopharyngeal angiofibroma pubmed central pmc. Juvenile nasopharyngeal angiofibroma, surgical approach, recurrence, residual disease introduction juvenile nasopharyngeal angiofibroma jna is a relatively rare tumor occurring mainly in adolescent boys. The evidence from these studies indicates that angiofibroma takes origin in the pterygopalatine fossa at the aperture of the pterygoid vidian canal. Pdf angiofibroma juvenil nasofaringeo researchgate. Despite tumor reduction with hormones, this approach is not routinely used. Nasoangiofibroma youth is a highly vascularized tumor almost exclusively male adolescents presentation. The classical clinical presentation of the angiofibroma is unilateral nasal block andor epistaxis, rhinorrhea, and occasionally pain.
The aim of this retrospective study was to compare clinical and radiological findings and discuss optimal surgical approach in patients with juvenile nasopharyngeal angiofibroma jna. Magnetic resonance imaging findings ayse gul alimli, murat ucar, cigdem oztunali, koray akkan, oznur boyunaga, cagr. As the tumor is largely spaceoccupying and highly vascular, patients typically. Juvenile nasopharyngeal angiofibroma jna is an uncommon, benign tumor of the nose that is generally seen in boys. Involution of residual juvenile nasopharyngeal angiofibroma volume 100 issue 5 j. Visual acuity was 2020 in both eyes and intraocular pressure iop 24 mmhg in left eye le without limitations in ocular movement. The juvenile nasopharyngeal angiofibroma is a benign neoplasm of the posterior.
Juvenile nasopharyngeal angiofibroma evaluation and workup return to. Jnas originate from the posterior choanal tissues and rapidly extend into the surrounding regions, including the nasopharynx, the orbits, and even the intracranial cavity. Vessels are thinwalled, lack elastic fibers, have absent or incomplete smooth muscle, and vary in appearance from stellate or staghorn to barely conspicuous because of stromal compression. Juvenile nasopharyngeal angiofibroma is a rare, benign tumor that occurs most often in adolescent males. It most commonly affects adolescent males because it is a hormonesensitive. Juvenile nasopharyngeal angiofibroma jna is a rare tumor in adolescent males. Well circumscribed, variable pseudocapsule cellular tumor with fascicles or haphazard pattern. Diagnosis and treatment of juvenile nasopharyngeal. They concluded that juvenile angiofibroma jna growth and vascularization are driven by factors released from stromal fibroblasts.
Frequently, the term juvenile is not included in the name of this tumor because this lesion may occur in adults occasionally, as well as in adolescents. Involution of residual juvenile nasopharyngeal angiofibroma the. Juvenile angiofibroma is a rare benign lesion originating from the pterygopalatine fossa with distinctive epidemiologic features and growth patterns. We aimed to report the characteristic magnetic resonance imaging mri findings and the spread patterns of jna. A sevenyear experience with patients with juvenile nasopharyngeal. Classically adolescent males with recurrent nose bleeds. Juvenile nasopharyngeal angiofibroma jna is a rare and benign but locally aggressive fibrovascular tumor arising from the posterolateral wall of the.
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